Randomized Trial of Hyperimmune Globulin for Congenital CMV Infection — 2-Year Outcomes

In this follow-up report of a trial of CMV hyperimmune globulin in pregnant women with primary CMV infection, hyperimmune globulin did not improve hearing or developmental outcomes in children at the age of 2 years.

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Bibliographic Details
Published in:The New England journal of medicine Vol. 389; no. 19; pp. 1822 - 1824
Main Authors: Hughes, Brenna L., Clifton, Rebecca G., Rouse, Dwight J., Saade, George R., Dinsmoor, Mara J., Reddy, Uma M., Pass, Robert, Allard, Donna, Mallett, Gail, MacPherson, Cora, Wapner, Ronald, Metz, Torri, Goodnight, William H., Tita, Alan T.N., Costantine, Maged M., Swamy, Geeta K., Heyborne, Kent D., Chien, Edward K., Chauhan, Suneet P., El-Sayed, Yasser Y., Casey, Brian M., Parry, Samuel, Simhan, Hyagriv N., Napolitano, Peter G., Macones, George A.
Format: Journal Article
Language:English
Published: United States Massachusetts Medical Society 09-11-2023
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Summary:In this follow-up report of a trial of CMV hyperimmune globulin in pregnant women with primary CMV infection, hyperimmune globulin did not improve hearing or developmental outcomes in children at the age of 2 years.
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ObjectType-Correspondence-1
A list of the members of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal–Fetal Medicine Units Network is provided in the Supplementary Appendix, available at NEJM.org.
ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMc2308286