Achondroplasia with multiple supplemental supernumerary teeth and multiple talon cusps: A rare case report

• Published in: Dental research journal Vol. 14; no. 3; pp. 219 - 222
• Main Authors: Raviraj, Jayam, Suman, Venkata, Suresh, Dirasantchu, Kartik, K
• Format: Journal Article
• Language: English
• Published: Iran Medknow Publications and Media Pvt. Ltd 01-05-2017; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd
• Subjects: Achondroplasia; Analysis; Case Report; Case reports; Consent; Dwarfism; Endocrine therapy; Fibroblast growth factors; Fibroblasts; Gene mutation; Genetic aspects; Growth factors; Growth hormones; Health aspects; Mandible; Mutation; Risk factors; Supernumerary; Supernumerary teeth; Teeth; Achondroplasia; dental; supernumerary teeth; dwarfism
• ISSN: 1735-3327; 2008-0255
• DOI: 10.4103/1735-3327.208769

Achondroplasia is the most common cause of dwarfism, which is inherited as an autosomal dominant disorder, caused by genetic mutation in fibroblast growth factor 3, leading to defective maturation of chondrocytes. It is known to be associated with various oral and dental manifestations such as delayed dental development, midfacial hypoplasia and constricted maxilla with a relatively large mandible, resulting in skeletal/dental Class III malocclusion, posterior crossbite, anterior reverse jet and anterior overbite. However, the association of achondroplasia with talon cusp and supernumerary teeth has never been reported in the literature. Wehereby reported a case of achondroplasia associated with such unusual findings. Moreover, all the three variants of talon cusp, i.e., "true talon,""semitalon" and "trace talon" are observed in the present case, which makes it a unique one. Further double talon cusps were noticed in the palatal aspect of maxillary central incisors.