High density of FOXP3 predicts better prognosis in germinal and non‐germinal centre diffuse large B‐cell lymphoma

This study highlights the prognostic impact of FOXP3 and CD68 expression in DLBCL, NOS and in its GCB and non‐GCB subtypes. This may help the development of individualized therapy, prognostic prediction and therapy stratification.

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Bibliographic Details
Published in:	International journal of experimental pathology Vol. 104; no. 3; pp. 128 - 139
Main Authors:	Ahmed, Asmaa M., Abdel‐Hakeem, Sally S., Amine, Maged A. F., Yassin, Etemad H., Badary, Fatma A. M.
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01-06-2023 John Wiley and Sons Inc
Subjects:	B-cell lymphoma CD68 DLBCL lymphoma Forkhead Transcription Factors - metabolism FOXP3 Foxp3 protein GCB Germinal Center - metabolism Germinal Center - pathology Germinal centers Humans Lymphoma Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - pathology Original Prognosis CD68 FOXP3 DLBCL lymphoma GCB
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Description
Summary:	This study highlights the prognostic impact of FOXP3 and CD68 expression in DLBCL, NOS and in its GCB and non‐GCB subtypes. This may help the development of individualized therapy, prognostic prediction and therapy stratification.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0959-9673 1365-2613
DOI:	10.1111/iep.12477