Polyserositis as a rare component of polyglandular autoimmune syndrome type II

• Published in: International journal of clinical practice (Esher) Vol. 55; no. 4; p. 280
• Main Authors: Algün, E, Erkoç, R, Kotan, C, Güler, N, Sahin, I, Ayakta, H, Uygan, I, Dilek, I, Aksoy, H
• Format: Journal Article
• Language: English
• Published: England 01-05-2001
• Subjects: Adult; Diabetes Mellitus, Type 1 - etiology; Diagnosis, Differential; Graves Disease - etiology; Humans; Male; Pericardial Effusion - complications; Pericardial Effusion - diagnostic imaging; Polyendocrinopathies, Autoimmune - complications; Serositis - etiology; Ultrasonography
• ISSN: 1368-5031
• DOI: 10.1111/j.1742-1241.2001.tb11035.x

Polyglandular autoimmune (PGA) syndromes (types I and II) may affect various endocrine and non-endocrine organs in the body. In the commoner PGA type II, primary adrenal insufficiency, autoimmune thyroid disease and type I diabetes mellitus are the most frequent manifestations. Serositis with pericardial or pleural involvement is not a well known component of the disease. Here, we report a 21-year-old man who first presented with a pleuropericardial effusion and Graves' disease, and who then developed type I diabetes mellitus.