Global burden of lung cancer in women of childbearing age attributable to ambient particulate matter pollution: 1990–2021

• Published in: Cancer medicine (Malden, MA) Vol. 13; no. 18; pp. e70241 - n/a
• Main Authors: Song, Ying‐da, Wang, Ruizhe, Wang, Jia‐xuan, Tan, Xun‐wu, Ma, Jun
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01-09-2024; John Wiley and Sons Inc; Wiley
• Subjects: Adolescent; Adult; Age groups; Air Pollutants - adverse effects; Air Pollutants - analysis; Air pollution; Air Pollution - adverse effects; ambient particulate matter air pollution; Disability-Adjusted Life Years; Disease; Environmental Exposure - adverse effects; Epidemiology; Female; Global Burden of Disease - trends; Global Burden of Disease 2021; Global health; Global Health - statistics & numerical data; Households; Humans; Lung cancer; Lung Neoplasms - chemically induced; Lung Neoplasms - epidemiology; Lung Neoplasms - etiology; Lung Neoplasms - mortality; Middle Aged; Mortality; Outdoor air quality; Particulate matter; Particulate Matter - adverse effects; Particulate Matter - analysis; Pollution; Population; Risk factors; Software; Trends; women of childbearing age; Womens health; Young Adult; lung cancer; epidemiology; ambient particulate matter air pollution; women of childbearing age; Global Burden of Disease 2021
• ISSN: 2045-7634; 2045-7634
• DOI: 10.1002/cam4.70241

Background
This study aimed to evaluate the global burden of lung cancer due to ambient particulate matter (PM) pollution in women of childbearing age from 1990 to 2021.
Methods
This was a secondary analysis utilizing data from the Global Burden of Disease (GBD) 2021, with a focus on the temporal trends of the lung cancer burden attributable to ambient PM2.5 among women of childbearing age.
Results
In 2021, the global mortality and disability‐adjusted life years (DALYs) number of lung cancer burden attributable to ambient PM2.5 among women of childbearing age were approximately 5205 and 247,211, respectively. The rate of lung cancer attributable to ambient PM2.5 among women of childbearing age increased between 1990 and 2021, with the age‐standardized mortality rate (ASMR) increasing from 0.22 (95% uncertainty interval [UI]; 0.13 to 0.33) to 0.25 (95% UI; 0.14 to 0.37; average annual percent change [AAPC] = 0.40) and the age‐standardized DALYs rate (ASDR) increasing from 10.39 (95% UI; 5.96 to 15.72) to 12.06 (95% UI; 6.83 to 17.51; AAPC = 0.41). The middle sociodemographic index (SDI) region, East Asia, and China had the heaviest burden, while the high SDI region showed the highest decrease. ASMR and ASDR exhibited an inverted U‐shaped relationship with the SDI.
Conclusions
From 1990 to 2021, the lung cancer burden attributable to ambient PM2.5 among women of childbearing age exhibited an increasing trend. Furthermore, increasing attention should be paid to the middle SDI region, East Asia, and China, as ambient PM pollution remains a critical target for intervention.