Control of the synovium in haemophilia

• Published in: Haemophilia : the official journal of the World Federation of Hemophilia Vol. 4; no. 4; pp. 511 - 513
• Main Authors: Lee, C. A., Kessler, C. M., Varon, D., Martinowitz, U., Heim, M., EICKHOFF, H. H., RADERSCHADT, G., KOCH, W., BRACKMANN, H.-H.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01-07-1998
• Subjects: classification; Haemophilic synovitis; Hemophilia A - complications; Hemophilia A - pathology; Hemophilia A - physiopathology; Humans; Synovial Membrane - pathology; Synovitis - etiology; Synovitis - pathology; Synovitis - physiopathology; Synovitis - therapy; treatment
• ISSN: 1351-8216; 1365-2516
• DOI: 10.1046/j.1365-2516.1998.440511.x

Adequate factor substitution is a prerequisite for successful conservative or operative treatment of haemophilic synovitis. Subsequent prophylactic factor substitution can prevent further joint problems in the future. Orthopaedic treatment regimes are dependent on the classification of the synovitis and the stage of the arthropathy. Synovitis can be classified into acute and chronic forms. The arthropathy is classified according to Arnold and Hilgartner. When the synovitis has already become chronic, early arthroscopic synovectomy is recommended in order to prevent the otherwise inexorable progress of the arthropathy. Failure to treat in the early phase of the pathology causes problems in the correction of further stages. The progression of the joint disease can be shown both clincally and radiologically as the arthropathy develops, and influences the treatment.