Single Atom-Dispersed Silver Incorporated in ZIF-8-Derived Porous Carbon for Enhanced Photothermal Activity and Antibacterial Activities

• Published in: International journal of nanomedicine Vol. 19; pp. 4253 - 4261
• Main Authors: Zheng, Yutong, Cai, Xiaoyi, Chen, Gui, Xiang, Dexuan, Shi, Wei, Shen, Jianliang, Xiang, Bailin
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 01-01-2024; Dove; Dove Medical Press
• Subjects: Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; antibacterial; Carbon - chemistry; Carbon - pharmacology; Escherichia coli; Escherichia coli - drug effects; Imidazoles; Infrared Rays; Metal-Organic Frameworks - chemistry; Metal-Organic Frameworks - pharmacology; Methicillin; Microbial Sensitivity Tests; Original Research; photothermal; Porosity; Silver - chemistry; Silver - pharmacology; single-atom; Staphylococcus aureus - drug effects; Zeolites - chemistry; Zeolites - pharmacology; zif-8; Iran; China; photothermal; antibacterial; ZIF-8; Ag; Single-atom
• ISSN: 1178-2013; 1176-9114; 1178-2013
• DOI: 10.2147/IJN.S459176

Recently, Single-atom-loaded carbon-based material is a new environmentally friendly and stable photothermal antibacterial nanomaterial. It is still a great challenge to achieve single-atom loading on carbon materials.
Herein, We doped single-atom Ag into ZIF-8-derived porous carbon to obtain Ag-doped ZIF-8-derived porous carbon(Ag
-ZDPC). The as-prepared samples were characterized by XRD, XPS, FESEM, EDX, TEM, and HAADF-STEM which confirmed that the single-atom Ag successfully doped into the porous carbon. Further, the photothermal properties and antimicrobial activity of Ag
-ZDPC have been tested.
The results showed that the temperature increased by 30 °C after near-infrared light irradiation(1 W/cm
) for 5 min which was better than ZIF-8-derived porous carbon(ZDPC). It also exhibits excellent photothermal stability after the laser was switched on and off 5 times. When the Ag
-ZDPC concentration was greater than 50 µg/mL and the near-infrared irradiation was performed for 5 min, the growth inhibition of S. aureus and E. coli was almost 100%.
This work provides a simple method for the preparation of single-atom Ag-doped microporous carbon which has potential antibacterial application.