Randomized Trial of "Bleach Baths" Plus Routine Hygienic Measures vs Routine Hygienic Measures Alone for Prevention of Recurrent Infections

• Published in: Clinical infectious diseases Vol. 58; no. 5; pp. 679 - 682
• Main Authors: Kaplan, Sheldon L., Forbes, Andrea, Hammerman, Wendy A., Lamberth, Linda, Hulten, Kristina G., Minard, Charles G., Mason, Edward O.
• Format: Journal Article
• Language: English
• Published: Oxford OXFORD UNIVERSITY PRESS 01-03-2014; Oxford University Press
• Subjects: Adolescent; Bathing; Baths - methods; Biological and medical sciences; BRIEF REPORT; Chemicals; Child; Child health services; Child, Preschool; Children; Children & youth; Clinical trials; Disease prevention; Disinfectants - therapeutic use; Disinfection - methods; Female; Humans; Hygiene; Hypochlorite; Infant; Infections; Infectious diseases; Male; Medical sciences; Methicillin resistant staphylococcus aureus; Recurrence; Single-Blind Method; Skin; Sodium Hypochlorite - therapeutic use; Staphylococcal Infections - prevention & control; Staphylococcus aureus; Therapeutic baths; Treatment Outcome; Infection; Prevention; Drug combination; Relapse; Comparative study; recurrent infections; Staphylococcus aureus; bleach bath
• ISSN: 1058-4838; 1537-6591
• DOI: 10.1093/cid/cit764

Children with probable community-associated Staphylococcus aureus skin and soft tissue or invasive infections were randomized to routine daily hygienic measures with or without "bleach baths" twice a week for 3 months. Within 12 months, a medically attended recurrence occurred in 84 of 495 (17%) children using bleach baths compared to 103 of 492 (21%) of control participants (P = .15).