Hematopoietic and Nitrogen-Sparing Effect of Preparations from Hog Gastric Mucosa with High Content of Blood Group Substances

Hematopoietic and Nitrogen-Sparing Effect of Preparations from Hog Gastric Mucosa with High Content of Blood Group Substances

A mucin fraction with high content of A and H blood group substances was obtained from hog gastric mucosa. This fraction administered per os together with vitamin B12 in rats made anemic by phenylhydrazine injection shows a significant effect on the hematologic response in comparison with the animal...

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Bibliographic Details
Published in:Blood Vol. 13; no. 2; pp. 156 - 161
Main Authors: Cresseri, Angelo, Cantone, Aurelio, Piccinini, Franco, Capraro, Vittorio
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-02-1958
Subjects:
Anemia
Blood Group Antigens
Gastric Mucins - pharmacology
Gastric Mucosa
Hematopoiesis
Hematopoietic System
Nitrogen - metabolism
Old Medline
ANEMIA/experimental
BLOOD GROUPS
HEMOPOIESIS
GASTRIC MUCIN/effects
NITROGEN/metabolism
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Summary:A mucin fraction with high content of A and H blood group substances was obtained from hog gastric mucosa. This fraction administered per os together with vitamin B12 in rats made anemic by phenylhydrazine injection shows a significant effect on the hematologic response in comparison with the animal treated with vitamin B12 alone. The same fraction administered per os in cortisone-treated rats has also a significant nitrogen sparing action. The possible mechanisms and relationships of the observed biologic effects are briefly discussed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V13.2.156.156