Incidentally Detected Oropharyngeal Squamous Cell Carcinoma on 18F-Fluciclovine PET/CT

ABSTRACTWe present a case of oropharyngeal squamous cell carcinoma (SCC) of the tongue base incidentally detected on F-fluciclovine PET/CT. A 79-year-old man with history of locally advanced prostate cancer (Gleason score 4 + 5 = 9; cT2cN1M0) previously treated with androgen deprivation therapy (lup...

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Bibliographic Details
Published in:Clinical nuclear medicine Vol. 44; no. 5; pp. e367 - e369
Main Authors: Raghavan, Kesav, Wen, Kwun Wah, Small, Eric J, Ha, Patrick, Flavell, Robert R
Format: Journal Article
Language:English
Published: United States Copyright Wolters Kluwer Health, Inc. All rights reserved 01-05-2019
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Summary:ABSTRACTWe present a case of oropharyngeal squamous cell carcinoma (SCC) of the tongue base incidentally detected on F-fluciclovine PET/CT. A 79-year-old man with history of locally advanced prostate cancer (Gleason score 4 + 5 = 9; cT2cN1M0) previously treated with androgen deprivation therapy (luprolide + bicalutamide) presented with a slowly rising serum prostate-specific antigen over 3 years, concerning for recurrent disease. F-fluciclovine PET/CT, obtained to identify potential sites of recurrence, demonstrated prostate bed uptake with possible left seminal vesicle involvement. Additionally, an exophytic, tracer-avid right tongue base mass was incidentally noted and later confirmed to be p16+ SCC on biopsy.
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ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000002507