Magnetic separation: its application in mining, waste purification, medicine, biochemistry and chemistry

• Published in: Chemical Society reviews Vol. 46; no. 19; p. 5925
• Main Authors: Iranmanesh, M, Hulliger, J
• Format: Journal Article
• Language: English
• Published: England 02-10-2017
• Subjects: Biochemistry - methods; Biomedical Research - methods; Chemistry - methods; Humans; Macromolecular Substances - chemistry; Macromolecular Substances - isolation & purification; Magnetic Fields; Magnetite Nanoparticles - chemistry; Metals, Heavy - chemistry; Metals, Heavy - isolation & purification; Mining - methods; Nanoparticles - chemistry; Particle Size; Proteins - chemistry; Proteins - isolation & purification
• ISSN: 1460-4744
• DOI: 10.1039/c7cs00230k

The use of strong magnetic field gradients and high magnetic fields generated by permanent magnets or superconducting coils has found applications in many fields such as mining, solid state chemistry, biochemistry and medical research. Lab scale or industrial implementations involve separation of macro- and nanoparticles, cells, proteins, and macromolecules down to small molecules and ions. Most promising are those attempts where the object to be separated is attached to a strong magnetic nanoparticle. Here, all kinds of specific affinity interactions are used to attach magnetic carrier particles to mainly objects of biological interest. Other attempts use a strong paramagnetic suspension for the separation of purely diamagnetic objects, such as bio-macromolecules or heavy metals. The application of magnetic separation to superconducting inorganic phases is of particular interest in combination with ceramic combinatorial chemistry to generate a library of e.g. cuprate superconductors.