Catheter-associated and nosocomial urinary tract infections: antibiotic resistance and influence on commonly used antimicrobial therapy

• Published in: International urology and nephrology Vol. 41; no. 3; pp. 461 - 464
• Main Authors: Milan, Potic B., Ivan, Ignjatovic M.
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 2009; Springer Nature B.V
• Subjects: Anti-Bacterial Agents - therapeutic use; Catheter-Related Infections - drug therapy; Catheter-Related Infections - microbiology; Cross Infection - drug therapy; Cross Infection - microbiology; Drug Resistance, Bacterial; Escherichia coli; Female; Humans; Klebsiella; Male; Medicine; Medicine & Public Health; Nephrology; Prospective Studies; Pseudomonas; Urinary Tract Infections - drug therapy; Urinary Tract Infections - microbiology; Urology; Urology - Original Paper; Community infection; Nosocomial infection; Empirical therapy
• ISSN: 0301-1623; 1573-2584
• DOI: 10.1007/s11255-008-9468-y

The objective is to evaluate resistance between community-acquired urinary tract infections (CAUTI), nosocomialy-acquired urinary tract infections (NAUTI), and empirical therapy adequacy.
E. coli
is the predominant pathogen of both CAUTI and NAUTI, followed by
Klebsiella
spp. in NAUTI and
Pseudomonas
spp. in catheter-associated urinary tract infections. The highest level of general resistance was found among isolates of NAUTI and catheter-associated UTI followed by CAUTI isolates. Absolute or high level resistance for commonly used empirical antimicrobial therapy was found in catheter-associated UTI and NAUTI while resistance among CAUTI was respectable. Patients with NAUTI as well as patients with catheter-associated urinary tract infections have similar resistance and similar microorganisms isolated as a causative agents, and should not be empirically treated unless the clinical emergency requests.