Application of Atmospheric Solids Analysis Probe Mass Spectrometry (ASAP-MS) in Petroleomics: Analysis of Condensed Aromatics Standards, Crude Oil, and Paraffinic Fraction

• Published in: Journal of the American Society for Mass Spectrometry Vol. 28; no. 11; pp. 2401 - 2407
• Main Authors: Tose, Lilian V., Murgu, Michael, Vaz, Boniek G., Romão, Wanderson
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-11-2017; Springer Nature B.V
• Subjects: Analytical Chemistry; Bioinformatics; Biotechnology; CHEMICAL COMPOSITION; Chemistry; Chemistry and Materials Science; Crude oil; Desorption; DETECTION; FOURIER TRANSFORMATION; FRAGMENTATION; Heating rate; INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; ION CYCLOTRON-RESONANCE; IONIZATION; Ions; Mass spectrometry; MASS SPECTROSCOPY; MOLECULAR WEIGHT; Organic Chemistry; PARAFFIN; POLYCYCLIC AROMATIC HYDROCARBONS; Proteomics; Research Article; SAMPLE PREPARATION; Scientific imaging; SOLIDS; Spectroscopy; TEMPERATURE GRADIENTS; Hydrocarbons; ASAP(+)-MS; Crude oil; Condensed aromatics
• ISSN: 1044-0305; 1879-1123
• DOI: 10.1007/s13361-017-1764-2

Atmospheric solids analysis probe mass spectrometry (ASAP-MS) is a powerful tool for analysis of solid and liquid samples. It is an excellent alternative for crude oil analysis without any sample preparation step. Here, ASAP-MS in positive ion mode, ASAP(+)-MS, has been optimized for analysis of condensed aromatics (CA) standards, crude oil, and paraffinic fraction samples using a Synapt G2-S HDMS. Initially, two methodologies were used to access the chemical composition of samples: (1) using a temperature gradient varying from 150 to 600 °C at a heating rate of 150 °C min
–1
, and (2) with constant temperature of 300 and 400 °C. ASAP(+)-MS ionized many compounds with a typical petroleum profile, showing a greater signals range of
m/z
250–1300 and 200–1400 for crude oil and paraffin samples, respectively. Such performance, mainly related to the detection of high molecular weight compounds (>1000 Da), is superior to that of other traditional ionization sources, such as ESI, APCI, DART, and DESI. Additionally, the CA standards were identified in both forms: radicals, [M]
+•
, and protonated cations, [M + H]
+
, with minimum fragmentation. Therefore, ASAP was more efficient in accessing the chemical composition of nonpolar and polar compounds. It is promising in its application with ultrahigh resolution MS instruments, such as FT-ICR MS and Orbitrap, since molecular formulas with greater resolution and mass accuracy (<1 ppm) would be assigned.
Graphical Abstract
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