Pathologic measures of quality compare favorably in patients undergoing robot-assisted radical cystectomy to open cystectomy cohorts: a National Cancer Database analysis

• Published in: Journal of robotic surgery Vol. 14; no. 4; pp. 609 - 614
• Main Authors: Miguel, Carla M., Kosinski, Kaitlin E., Fazzari, Melissa J., Kongnyuy, Michael, Smaldone, Marc C., Schiff, Jeffrey T., Katz, Aaron E., Corcoran, Anthony T.
• Format: Journal Article
• Language: English
• Published: London Springer London 01-08-2020; Springer Nature B.V
• Subjects: Bladder cancer; Cancer; Cancer therapies; Community centers; Dissection; Histology; Hospitals; Lymphatic system; Medicine; Medicine & Public Health; Minimally Invasive Surgery; Original Article; Patients; Regression models; Robotic surgery; Surgery; Trends; Urological surgery; Urology; Variables; United States > US; Open radical cystectomy; Muscle invasive bladder cancer; Radical cystectomy; Robot-assisted
• ISSN: 1863-2483; 1863-2491
• DOI: 10.1007/s11701-019-01031-z

This study aims to assess the impact of facility characteristics on measures of surgical quality (positive surgical margin rates and lymph-node yield) in patients undergoing robot-assisted (RARC) versus open (ORC) radical cystectomy using the National Cancer Database. Patients who received RC between the years of 2010–2013 were stratified according to surgery type (ORC vs. RARC), and corresponding patient and facility-level variables (facility type and volume) were assessed. Logistic regression models for procedure type, positive surgical margins (PSMs), and LN dissection (LND) rates were estimated. Radical cystectomies (ORC = 13,236, RARC = 3687) were performed more often in academic centers (58.3%) compared to community centers (31.6%). As facility volume increased, centers performed more LNDs during ORCs (
p
 = 0.03) and the number of nodes retrieved increased in both ORC and RARC (ORC
p
 < 0.001; RARC
p
 < 0.0001). Increased facility volume also resulted in significantly fewer PSMs within the RARC cohort (
p
 = 0.01). Comparison of ORC and RARC within each facility type cohort identified improved pathological metrics for RARC with fewer PSMs (
p
 = 0.001) as well as increased LNDs (
p
 < 0.0001) and median number of LNs retrieved (
p
 < 0.0001), which suggests that RARC may facilitate comparative outcomes in community centers and academic centers. Overall, higher facility volume and robot-assisted surgery resulted in more favorable pathologic metrics compared to lower facility volume and ORC.