Drosophila Mechanotransduction-Linking Proteins and Functions

Drosophila Mechanotransduction-Linking Proteins and Functions

The sensation of touch, gravity, and sound all rely on dedicated ion channels that transduce mechanical stimulus forces into electrical response signals. The functional workings and molecular identities of these mechanotransducer channels are little understood. Recent work shows that the mechanotran...

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Bibliographic Details
Published in:Fly (Austin, Tex.) Vol. 1; no. 4; pp. 238 - 241
Main Authors: Albert, Jörg T., Nadrowski, Björn, Göpfert, Martin C.
Format: Journal Article
Language:English
Published: United States Taylor & Francis 01-07-2007
Subjects:
Animals
Binding
Biology
Bioscience
Calcium
Cancer
Cell
Cycle
Drosophila melanogaster - physiology
Drosophila Proteins - physiology
Ear - physiology
Hearing
Landes
Mechanotransduction, Cellular
Organogenesis
Proteins
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Summary:The sensation of touch, gravity, and sound all rely on dedicated ion channels that transduce mechanical stimulus forces into electrical response signals. The functional workings and molecular identities of these mechanotransducer channels are little understood. Recent work shows that the mechanotransducers for fly and vertebrate hearing share equivalent gating mechanisms, whereby this mechanism can be probed non-invasively in the mechanics of the Drosophila ear. Here, we describe how this mechanics can be used to evaluate the roles of identified proteins in the process of mechanosensation and, specifically, their contributions to mechanotransduction.
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ISSN:1933-6934
1933-6942
DOI:10.4161/fly.4990