MicroRNAs in Atrial Fibrillation: Pathophysiological Aspects and Potential Biomarkers

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia associated with increased morbidity and mortality. The pathophysiological mechanisms underlying the development of AF are not entirely clear. In addition, there are no optimal biomarkers for the early detection and prognosis fo...

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Bibliographic Details
Published in:	International journal of biomedicine Vol. 10; no. 3; pp. 198 - 205
Main Authors:	Chaulin, Aleksey, Duplyakov, Dmitriy
Format:	Journal Article
Language:	English
Published:	International Medical Research and Development Corporation 01-09-2020
Subjects:	atrial fibrillation biomarker microrna pathophysiology
Online Access:	Get full text
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Summary:	Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia associated with increased morbidity and mortality. The pathophysiological mechanisms underlying the development of AF are not entirely clear. In addition, there are no optimal biomarkers for the early detection and prognosis for patients with AF. Emerging studies have uncovered a role for miRNAs in the initiation and maintenance of CVD. This review discusses the role of miRNAs in the pathogenesis of AF as well as the possibility of using miRNAs as biomarkers for detecting and predicting AF.
ISSN:	2158-0510 2158-0529
DOI:	10.21103/Article10(3)_RA3