Prevalence of Metabolic Syndrome in Patients With Intermittent Claudication and its Correlation With the Segment of Arterial Obstruction

• Published in: Angiology Vol. 61; no. 8; pp. 784 - 788
• Main Authors: Zerati, Antonio Eduardo, Wolosker, Nelson, Ayzin Rosoky, Ruben Miguel, Fernandes Saes, Glauco, Ragazzo, Luciana, Puech-Leão, Pedro
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01-11-2010; Sage Publications
• Subjects: Adult; Aged; Aged, 80 and over; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Cardiovascular system; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Female; Humans; Intermittent Claudication - complications; Intermittent Claudication - pathology; Leg - blood supply; Male; Medical sciences; Metabolic Syndrome - complications; Metabolic Syndrome - diagnosis; Middle Aged; Peripheral Vascular Diseases - complications; Peripheral Vascular Diseases - pathology; Pharmacology. Drug treatments; Vasodilator agents. Cerebral vasodilators; Waist-Hip Ratio; atherosclerosis; metabolic syndrome; peripheral arterial disease; claudication; insulin resistance; Endocrinopathy; Human; Claudication; Prevalence; Intermittent; Metabolic diseases; Cardiovascular disease; Metabolic syndrome; Obstruction
• ISSN: 0003-3197; 1940-1574
• DOI: 10.1177/0003319710366127

The metabolic syndrome (MetS) is associated with increased cardiovascular morbidity and mortality. Intermittent claudication reflects the presence of peripheral arterial disease (PAD). The aim of this study is to determine the prevalence of the MetS in claudicants and its correlation with age, gender, localization of arterial obstruction, and symptomatic coronary disease. Patients (n = 170) with intermittent claudication were studied. The mean age was 65 years (33-89). Metabolic syndrome was diagnosed in 98 patients (57.6%). The mean age of patients with MetS was 63.5 years compared with 67.0 years for patients without MetS (P = .027). Considering patients aged ≥65 years, MetS was present in 46 (48.9%) individuals and in 52 (68.4%) patients younger than 65 years (P = .011). Metabolic syndrome must be actively searched for in claudicant patients.