'Upgrading' psoriasis responsibly

Psoriasis is a ‘pacemaker’ in dermatology. Substantial progress has been made regarding our understanding of its pathophysiology and genetic background, fuelling developments in cutaneous biology in general. Besides, the clinical perspective on psoriasis is currently changing, taking into considerat...

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Published in:Experimental dermatology Vol. 23; no. 10; pp. 710 - 711
Main Authors: Boehncke, Sandra, Boehncke, Wolf-Henning
Format: Journal Article
Language:English
Published: Denmark Blackwell Publishing Ltd 01-10-2014
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Summary:Psoriasis is a ‘pacemaker’ in dermatology. Substantial progress has been made regarding our understanding of its pathophysiology and genetic background, fuelling developments in cutaneous biology in general. Besides, the clinical perspective on psoriasis is currently changing, taking into consideration comorbidity and the systemic dimensions of this seemingly organ‐specific inflammation. The availability of drugs exhibiting fewer contraindications and improved long‐term safety opened a discussion around replacing a relatively limited (regarding both objectives and duration) ‘therapeutic’ by a much broader ‘management’ approach when it comes to treating psoriasis as a systemic disease. The question arises whether this ‘upgrade’ is warranted.
Bibliography:ark:/67375/WNG-4J8VJG46-2
ArticleID:EXD12494
istex:072AD9F431E46CA8C2E28B5CEC2BF2FC889BCDFB
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Commentary-1
ISSN:0906-6705
1600-0625
DOI:10.1111/exd.12494