Radiofrequency electromagnetic field affects heart rate variability in rabbits

• Published in: Physiological research Vol. 69; no. 4; pp. 633 - 643
• Main Authors: Misek, J, Veterník, M, Tonhajzerova, I, Jakusova, V, Janousek, L, Jakus, J
• Format: Journal Article
• Language: English
• Published: Czech Republic Institute of Physiology 31-08-2020; Institute of Physiology of the Czech Academy of Sciences
• Subjects: Anesthesia; Animals; Antennas; Arrhythmias, Cardiac - etiology; Arrhythmias, Cardiac - pathology; Cell Phone - instrumentation; Double-Blind Method; Electromagnetic fields; Electromagnetic Fields - adverse effects; Electromagnetism; Environmental Exposure - adverse effects; General anesthesia; Heart rate; Heart Rate - physiology; Heart Rate - radiation effects; Low frequency; Models, Animal; Ostomy; Rabbits; Radio Waves - adverse effects; Random Allocation; Receivers & amplifiers; Vagus nerve; New Zealand; United States > US
• ISSN: 0862-8408; 1802-9973
• DOI: 10.33549/physiolres.934425

The aim of this study was to assess the effects of radiofrequency electromagnetic field (RF EMF) on heart rate variability (HRV) in rabbits with intensity slightly exceeding the limits for occupations. Totally 21 New Zealand white rabbits divided into two groups were used in this double-blind study. The first group of animals without general anesthesia was subjected to HRV examination under exposure to a device generated RF EMF source (frequency 1788 MHz, intensity 160 V/m, lasting 150 min.). The second group (premedications + alpha chloralose mg/kg) underwent the same protocol under the exposure to the real RF EMF signal from the base stations of mobile providers (frequency range 1805 - 1870 MHz - corresponding to the downlink signal of Slovak mobile providers, 160 V/m, 150 min., respectively). Individual 5 min records were used to analyze the HRV parameters: heart rate and root Mean Square of the Successive Differences (rMSSD) for time domain analysis and spectral powers in the low (LF-VFS) and high frequency (HF-VFS) bands for frequency domain analysis. Our study revealed the increased in HRV parameters (HF-HRV, rMSSD) associated with lower heart rate indicating increased cardiac vagal control under the exposure to RF EMF in experimental methods.