Estimation of hepatic fat fraction using modified Dixon magnetic resonance imaging techniques: effect of liver cirrhosis

• Published in: Clinical imaging Vol. 51; pp. 50 - 58
• Main Authors: Min, Jeeyoung, Park, Hee Sun, Kim, Young Jun, Yu, Mi Hye, Jung, Sung Il, Jeon, Hae Jeong
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-09-2018; Elsevier Limited
• Subjects: Accuracy; Adipose Tissue - metabolism; Adult; Aged; Cirrhosis; Fatty Liver - diagnostic imaging; Female; Hepatic steatosis; Hepatitis; Humans; Imaging techniques; Liver; Liver - metabolism; Liver - pathology; Liver cancer; Liver cirrhosis; Liver Cirrhosis - complications; Liver diseases; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Magnetic resonance spectroscopy; Magnetic Resonance Spectroscopy - methods; Male; Medical imaging; Middle Aged; Multi-echo Dixon; NMR; Nuclear magnetic resonance; Patients; Reproducibility of Results; Magnetic resonance spectroscopy; Cirrhosis; Multi-echo Dixon; Hepatic steatosis; Magnetic resonance imaging
• ISSN: 0899-7071; 1873-4499
• DOI: 10.1016/j.clinimag.2018.02.002

To evaluate modified Dixon MRI techniques in hepatic fat estimation and to assess the effect of cirrhosis.
235 patients who underwent liver MRI were included. Correlation between modified Dixon techniques with MRS was assessed. Accuracy of MR techniques in hepatic fat estimation was calculated, and the result was compared between patients with/without liver cirrhosis.
Correlation between modified Dixon and MRS was better in group without liver cirrhosis, and accuracy of modified Dixon method was higher in group without liver cirrhosis.
Modified Dixon techniques estimate hepatic fat fraction noninvasively, but the result can be influenced by the presence of liver cirrhosis.
•Modified Dixon techniques and MRS showed strong positive correlation in all patients in hepatic fat quantification.•In hepatic fat quantification, correlation between dual-echo Dixon and MRS was better in the absence of liver cirrhosis than in those with liver cirrhosis.•Accuracy of modified Dixon techniques in hepatic fat estimation was higher in group without liver cirrhosis than in those with liver cirrhosis.