A novel HLA-B40 allele, B40:01:40, identified in a Chinese individual

Summary A new allele, officially named B*40:01:40, was detected in a Chinese individual by sequence‐based typing (SBT). The new allele differs from B*40:01:01 by a single nucleotide exchange at position 99 in codon 9, which results in synonymous substitution and seems not to compromise the HLA compl...

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Bibliographic Details
Published in:	International journal of immunogenetics Vol. 43; no. 4; pp. 249 - 250
Main Authors:	Pei, Y. F., Huang, H. N., Li, H. C., Shen, W. D.
Format:	Journal Article
Language:	English
Published:	England Blackwell Publishing Ltd 01-08-2016
Subjects:	Alleles Amino Acid Substitution - genetics Amino Acid Substitution - immunology Asian Continental Ancestry Group China Codon - genetics HLA-B Antigens - genetics HLA-B Antigens - immunology HLA-B Antigens - isolation & purification Humans Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - immunology
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Summary:	Summary A new allele, officially named B40:01:40, was detected in a Chinese individual by sequence‐based typing (SBT). The new allele differs from B40:01:01 by a single nucleotide exchange at position 99 in codon 9, which results in synonymous substitution and seems not to compromise the HLA complex and T‐cell receptor interaction.
Bibliography:	ark:/67375/WNG-F49BXJZP-C Science research and technology development project of Nanning - No. 201003048 C-3 istex:8435D42FE032854228BF1B6FA6A2978B4BFE0DED ArticleID:IJI12279 The CMDP high-resolution typing contract ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1744-3121 1744-313X
DOI:	10.1111/iji.12279