Hyperthyroidism and Lupus‐like Syndrome in an Adolescent Treated with Minocycline for Acne Vulgaris

• Published in: Pediatric dermatology Vol. 24; no. 3; pp. 246 - 249
• Main Authors: Benjamin, Robert W., Calikoglu, Ali S.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01-05-2007; Blackwell
• Subjects: Acne Vulgaris - drug therapy; Adolescent; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - adverse effects; Biological and medical sciences; Dermatology; Endocrinopathies; Humans; Hyperthyroidism - chemically induced; Lupus Erythematosus, Systemic - chemically induced; Male; Medical sciences; Minocycline - administration & dosage; Minocycline - adverse effects; Non tumoral diseases. Target tissue resistance. Benign neoplasms; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Skin involvement in other diseases. Miscellaneous. General aspects; Tachycardia - chemically induced; Thyroid. Thyroid axis (diseases); Endocrinopathy; Human; Connective tissue disease; Pediatrics; Skin disease; Dermatology; Tetracycline derivatives; Hyperthyroidism; Thyroid diseases; Acne vulgaris; Antibiotic; Lupus like syndrome; Treatment; Systemic disease; Adolescent; Minocycline; Protein synthesis inhibitor; Antibacterial agent
• ISSN: 0736-8046; 1525-1470
• DOI: 10.1111/j.1525-1470.2007.00395.x

:  Minocycline is a tetracycline antibiotic commonly used in the treatment of acne. While it is generally considered to be a safe medicine, a number of side effects have been associated with its use. We describe an adolescent boy who developed hyperthyroidism and a drug‐induced lupus‐like syndrome following minocycline treatment for his acne.