Immunologic and Virologic Outcomes of Obese and Nonobese Incarcerated Adults on Antiretroviral Therapy for HIV Infection

• Published in: Journal of the International Association of Providers of AIDS Care Vol. 17; p. 2325957417752261
• Main Authors: Bunnell, Kristen L., Aldossari, Arwa, Perkins, Connor, Schriever, Christopher, Chiampas, Thomas D., Young, Jeremy D., Patel, Mahesh C., Badowski, Melissa
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01-01-2018; SAGE PUBLICATIONS, INC; SAGE Publishing
• Subjects: Antiretroviral drugs; Antiretroviral therapy; Body weight; Drug therapy; HIV; Human immunodeficiency virus; Imprisonment; Medical technology; Obesity; Patients; Prescription drugs; Short Communication; Telecommunications; HIV infection; antiretroviral therapy; obesity
• ISSN: 2325-9582; 2325-9574; 2325-9582
• DOI: 10.1177/2325957417752261

Background:
Obesity is common among patients with HIV. The objective of this study was to characterize response to antiretroviral therapy (ART) in a cohort of obese incarcerated adults compared to a nonobese cohort.
Methods:
A retrospective matched cohort study was conducted in an HIV telemedicine clinic. Patients with body mass index (BMI) >30 kg/m2 who received the same ART with >95% adherence for at least 6 months were matched to nonobese patients by age, gender, ART, CD4 count, and viral load at baseline.
Results:
Twenty pairs were included, with an average BMI of 24 kg/m2 in the nonobese cohort and 35 kg/m2 in the obese cohort. No difference was observed in the proportion of patients who achieved virologic suppression or the change in CD4 count from baseline to 6 to 12 months.
Conclusion:
This study revealed no differences in immunologic recovery or virologic suppression between obese and nonobese patients in an adult correctional population.