Assignment of the mouse tartrate-resistant acid phosphatase gene (Acp5) to chromosome 9

Assignment of the mouse tartrate-resistant acid phosphatase gene (Acp5) to chromosome 9

Tartrate-resistant acid phosphatase is a marker enzyme for osteoclasts, the multinucleated cell responsible for bone resorption. Interspecific somatic whole cell hybrids and karyotypically simple microcell hybrids were used to map the gene encoding tartrate-resistant acid phosphatase (Acp5) to mouse...

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Bibliographic Details
Published in:Genomics (San Diego, Calif.) Vol. 15; no. 2; p. 421
Main Authors: Grimes, R, Reddy, S V, Leach, R J, Scarcez, T, Roodman, G D, Sakaguchi, A Y, Lalley, P A, Windle, J J
Format: Journal Article
Language:English
Published: United States 01-02-1993
Subjects:
Acid Phosphatase - genetics
Animals
Base Sequence
Chromosome Mapping
Cricetinae
Cricetulus
DNA, Single-Stranded
Hybrid Cells
Mice
Molecular Sequence Data
Rats
Tartrates - pharmacology
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Summary:Tartrate-resistant acid phosphatase is a marker enzyme for osteoclasts, the multinucleated cell responsible for bone resorption. Interspecific somatic whole cell hybrids and karyotypically simple microcell hybrids were used to map the gene encoding tartrate-resistant acid phosphatase (Acp5) to mouse Chromosome 9. Acp5 is therefore a member of a syntenic family of genes that map to human chromosome 19p13.1-p13.3 and mouse Chromosome 9.
ISSN:0888-7543
DOI:10.1006/geno.1993.1079