Qualitative theoretical modeling to study the possibility of detecting multi-virus in blood flow using Nano-quartz crystal microbalance

• Published in: Mathematical biosciences and engineering : MBE Vol. 17; no. 5; pp. 4563 - 4577
• Main Authors: Abbas, Mohamed, Algahtani, Ali, Kessentini, Amir, Loukil, Hassen, Parayangat, Muneer, Ijyas, Thafasal, Wase Mohammed, Abdul
• Format: Journal Article
• Language: English
• Published: AIMS Press 01-09-2020
• Subjects: blood flow; heat transfer; laminar stream; quartz nanoparticles; virus detection
• ISSN: 1551-0018; 1551-0018
• DOI: 10.3934/mbe.2020252

Methods for testing the presence of a virus in the blood are of interest to researchers and doctors because they determine how rapidly a virus is detected. In general, virus detection is a major scientific problem due to the serious effects of viruses on the human body. At present, only one virus can be detected in a single test. This potentially costs the medical establishment more time and money that could be saved if blood testing was more efficient. This study presents a qualitative method to enable doctors and researchers to detect more than one virus simultaneously. This was performed using quartz nanoparticles. Using polymer thin films of polydimethylsiloxane (PDMS), each chip emits a different frequency for each specific type of virus on the chip. The multiplicity of these chips allows for the detection of a number of viruses with the same number of nanoscale chips simultaneously. Blood flow around quartz nanoparticles was modelled. In this model, several conventional Quartz Crystal Microbalance (QCM) with nanostructures (Nano-QCM) particles are inserted into the three main types of blood vessels. The results showed that the best location for the Nano-QCM is the large artery and that it is possible to test for a number of viruses in all types of blood vessels.