Heterochromatin: On the ADAR Radar?

Vigilin proteins, the absence of which is known to cause abnormalities in heterochromatin, have been found to bind edited RNAs. Molecular complexes including vigilin comprise proteins involved with RNA editing and with DNA repair, making connections between these processes and RNA-based silencing me...

Full description

Saved in:

Bibliographic Details
Published in:	Current biology Vol. 15; no. 4; pp. R132 - R134
Main Authors:	Fernandez, H.R., Kavi, H.H., Xie, W., Birchler, J.A.
Format:	Journal Article
Language:	English
Published:	England Elsevier Inc 22-02-2005
Subjects:	Autoantigens - metabolism Carrier Proteins - genetics Carrier Proteins - metabolism DEAD-box RNA Helicases DNA Repair DNA-Activated Protein Kinase DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Drosophila Proteins - genetics Drosophila Proteins - metabolism Heterochromatin - genetics Models, Biological Neoplasm Proteins Protein-Serine-Threonine Kinases - metabolism RNA - metabolism RNA Helicases - metabolism RNA Interference RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Vigilin proteins, the absence of which is known to cause abnormalities in heterochromatin, have been found to bind edited RNAs. Molecular complexes including vigilin comprise proteins involved with RNA editing and with DNA repair, making connections between these processes and RNA-based silencing mechanisms.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0960-9822 1879-0445
DOI:	10.1016/j.cub.2005.02.012