Efficient Aerobic Oxidation of trans‐2‐Hexen‐1‐ol using the Aryl Alcohol Oxidase from Pleurotus eryngii

The selective oxidation of trans‐2‐hexen‐1‐ol to the corresponding aldehyde using a recombinant aryl alcohol oxidase from Pleurotus eryngii (PeAAOx) is reported. Especially using the two liquid phase system to overcome solubility and product inhibition issues enabled to achieve more than 2.200.000 c...

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Bibliographic Details
Published in:	Advanced synthesis & catalysis Vol. 361; no. 11; pp. 2668 - 2672
Main Authors:	de Almeida, T. P., van Schie, M. M. C. H., Ma, A., Tieves, F., Younes, S. H. H., Fernández‐Fueyo, E., Arends, I. W. C. E., Riul, A., Hollmann, F.
Format:	Journal Article
Language:	English
Published:	Heidelberg Wiley Subscription Services, Inc 06-06-2019
Subjects:	Alcohol Alcohol oxidase Aldehydes Aromatic compounds biocatalysis Catalysis Liquid phases oxidase Oxidation oxidation reactions Product inhibition two liquid phase system
Online Access:	Get full text
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Summary:	The selective oxidation of trans‐2‐hexen‐1‐ol to the corresponding aldehyde using a recombinant aryl alcohol oxidase from Pleurotus eryngii (PeAAOx) is reported. Especially using the two liquid phase system to overcome solubility and product inhibition issues enabled to achieve more than 2.200.000 catalytic turnovers for the production enzyme as well as molar product concentrations, pointing towards an economic feasible reaction.
ISSN:	1615-4150 1615-4169
DOI:	10.1002/adsc.201801312