Occipitocervical fusion after resection of craniovertebral junction tumors

• Published in: Journal of neurosurgery. Spine Vol. 4; no. 2; pp. 137 - 144
• Main Authors: SHIN, Hyunchul, BARRENECHEA, Ignacio J, LESSER, Jonathan, SEN, Chandranath, PERIN, Noel I
• Format: Journal Article
• Language: English
• Published: Charlottesville, VA American Association of Neurological Surgeons 01-02-2006
• Subjects: Adolescent; Adult; Aged; Biological and medical sciences; Biomechanical Phenomena; Cervical Vertebrae - pathology; Cervical Vertebrae - surgery; Child; Chordoma - surgery; Female; Humans; Male; Medical sciences; Meningeal Neoplasms - surgery; Meningioma - surgery; Middle Aged; Neck Pain; Neoplasm Metastasis; Neurosurgery; Occipital Bone - pathology; Occipital Bone - surgery; Orthopedic surgery; Retrospective Studies; Risk Factors; Skull Base Neoplasms - surgery; Spinal Fusion - methods; Spinal Neoplasms - surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Treatment Outcome; fusion; Occipitocervical; extreme-lateral transcondylar approach; craniovertebral junction tumor; occipital condyle; Condyle; Occipital; Tumor; Surgical approach
• ISSN: 1547-5654; 1547-5646
• DOI: 10.3171/spi.2006.4.2.137

Surgical access to tumors at the craniovertebral junction (CVJ) requires extensive bone removal. Guidelines for the use of occipitocervical fusion (OCF) after resection of CVJ tumors have been based on anecdotal evidence. The authors performed a retrospective study of factors associated with the use of OCF in 46 patients with CVJ tumors. The findings were used to develop recommendations for use of OCF in such patients.
The authors retrospectively reviewed the cases of 51 patients with CVJ tumors treated by their group between March 1991 and February 2004. Forty-six patients were available for follow up. Charts were reviewed to obtain data on demographic characteristics, presenting symptoms, and perioperative complications. Preoperative computerized tomography scans and magnetic resonance imaging studies were obtained in all patients. Occipitocervical fusion was performed in patients who had undergone a unilateral condyle resection in which 70% or more of the condyle was removed, a bilateral condyle resection with 50% removal, or C1-2 vertebral body destruction. Of the 46 patients, 16 had foramen magnum meningiomas, 17 had chordomas, one had a chondrosarcoma, two had Schwann cell tumors, two had glomus tumors, and eight had other types of tumors. Twenty-three (50%) of the 46 patients underwent OCF, including 15 of the 17 patients with chordomas (88%). None of the patients with meningiomas required fusion. Seventeen (71%) of the 24 patients presenting with neck pain preoperatively underwent OCF.
Patients presenting with neck pain had a 71% chance of undergoing OCF. Patients with chordomas and metastatic tumors were most likely to require OCF. One patient with a 50% unilateral condylar resection returned with OC instability for which OCF was required. Based on their clinical experience and published biomechanical studies, the authors recommend that OCF be performed when 50% or more of one condyle is resected.