Growth hormone therapy for adult growth hormone deficiency

GH deficiency in adult life is associated with a number of adverse biological changes including osteopenia, reduced exercise capacity, altered body composition, deleterious alterations in the lipid profile and insulin status, and reduced quality of life. Potentially, most of these changes can be rev...

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Bibliographic Details
Published in:	Trends in Endocrinology & Metabolism Vol. 7; no. 8; pp. 287 - 290
Main Authors:	Shalet, Stephen M., Rahim, Asad, Toogood, Andrew A.
Format:	Book Review Journal Article
Language:	English
Published:	London Elsevier Ltd 01-10-1996 Elsevier
Subjects:	Biological and medical sciences Hormones. Endocrine system Medical sciences Pharmacology. Drug treatments Endocrinopathy Human Chemotherapy Replacement therapy Adenohypophyseal hormone Deficiency STH Adult Review
Online Access:	Get full text
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Summary:	GH deficiency in adult life is associated with a number of adverse biological changes including osteopenia, reduced exercise capacity, altered body composition, deleterious alterations in the lipid profile and insulin status, and reduced quality of life. Potentially, most of these changes can be reversed by GH replacement therapy. In an era of health rationing, however, GH replacement is unlikely to be offered to every GH-deficient adult. Therefore, we have proposed a strategy aimed at delineating which adults with GH deficiency might benefit most from GH therapy.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1043-2760 1879-3061
DOI:	10.1016/S1043-2760(96)00130-0