Influenza pandemic preparedness: gauging from EU plans

Influenza pandemic preparedness: gauging from EU plans

The possibility of avian influenza H5N1 virus converting into a pandemic form in human beings is an imminentthreat.Then again it might not assume pandemicity for some time, or not at all. Recently reported vaccine trial studies highlight immunogenicity problems.5 Moreover, multiple genetic and antig...

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Bibliographic Details
Published in:The Lancet (British edition) Vol. 367; no. 9520; pp. 1374 - 1375
Main Author: Shortridge, Kennedy F
Format: Journal Article
Language:English
Published: England Elsevier Ltd 29-04-2006
Elsevier Limited
Subjects:
Avian flu
Disaster Planning - organization & administration
Disease Outbreaks
Emergency preparedness
European Union
Humans
Immunization
Immunogenicity
Influenza A Virus, H5N1 Subtype - pathogenicity
Influenza, Human - epidemiology
Pandemics
Vaccines
Online Access:Get full text
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Summary:The possibility of avian influenza H5N1 virus converting into a pandemic form in human beings is an imminentthreat.Then again it might not assume pandemicity for some time, or not at all. Recently reported vaccine trial studies highlight immunogenicity problems.5 Moreover, multiple genetic and antigenic lineages of H5N1 complicate vaccine candidacy.4 Because immunisation is the most effective mechanism for blunting a pandemic, it would seem wise to reconsider plans as there may not be a vaccine available at whatever time a pandemic might arise.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Commentary-1
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(06)68512-7