Molecular diagnosis and precision medicine in allergy management

Precision medicine (PM) can be defined as a structural model aimed at customizing healthcare, with medical decisions/products tailored on an individual patient at a highly detailed level. In this sense, allergy diagnostics based on molecular allergen components allows to accurately define the patien...

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Bibliographic Details
Published in:	Clinical chemistry and laboratory medicine Vol. 54; no. 11; p. 1705
Main Authors:	Riccio, Anna Maria, De Ferrari, Laura, Chiappori, Alessandra, Ledda, Sabina, Passalacqua, Giovanni, Melioli, Giovanni, Canonica, Giorgio Walter
Format:	Journal Article
Language:	English
Published:	Germany 01-11-2016
Subjects:	Desensitization, Immunologic Humans Hypersensitivity - diagnosis Hypersensitivity - therapy Precision Medicine
Online Access:	Get more information
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Summary:	Precision medicine (PM) can be defined as a structural model aimed at customizing healthcare, with medical decisions/products tailored on an individual patient at a highly detailed level. In this sense, allergy diagnostics based on molecular allergen components allows to accurately define the patient's IgE repertoire. The availability of highly specialized singleplexed and multiplexed platforms support allergists with an advanced diagnostic armamentarium. The therapeutic intervention, driven by the standard diagnostic approach, but further supported by these innovative tools may result, for instance, in a more appropriate prescription of allergen immunotherapy (AIT). Also, the phenotyping of patients, which may have relevant effects on the treatment strategy, could be take advantage by the molecular allergy diagnosis.
ISSN:	1437-4331
DOI:	10.1515/cclm-2016-0007