Use of [18F]-fluorodeoxyglucose positron emission tomography in monitoring response of recurrent neurotropic desmoplastic melanoma to radiotherapy

• Published in: Otolaryngology-head and neck surgery Vol. 122; no. 2; pp. 304 - 306
• Main Authors: HANNAH, ANTHONY, FEIGEN, MALCOLM, QUONG, GEORGE, AKHURST, TIM, BERLANGIERI, SALVATORE U., ZIMET, ALLAN, ZALCBERG, JOHN, MCKAY, W.J., SCOTT, REW M.
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA Mosby, Inc 01-02-2000; SAGE Publications
• Subjects: Adult; Fluorodeoxyglucose F18; Humans; Male; Mandibular Neoplasms - diagnostic imaging; Mandibular Neoplasms - radiotherapy; Mandibular Neoplasms - secondary; Melanoma - diagnostic imaging; Melanoma - radiotherapy; Melanoma - secondary; Mouth Neoplasms - diagnostic imaging; Mouth Neoplasms - radiotherapy; Mouth Neoplasms - secondary; Neoplasm Recurrence, Local - diagnostic imaging; Neoplasm Recurrence, Local - radiotherapy; Radiopharmaceuticals; Skin Neoplasms - pathology; Tomography, Emission-Computed
• ISSN: 0194-5998; 1097-6817
• DOI: 10.1016/S0194-5998(00)70261-0

A 35-year-old man originally sought treatment in 1985 for an ulcerating lesion on the lower lip. When the lesion was resected, histology showed an amelanotic neurotropic variant of desmoplastic melanoma invading deep into the muscle of the lip around small nerves and blood vessels; staining was positive for S-100 protein. Repeat excisions were performed twice during the next 2 months, before histologically complete removal was attained.