Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy

• Published in: The New England journal of medicine Vol. 388; no. 23; pp. 2132 - 2144
• Main Authors: Simmons, David, Immanuel, Jincy, Hague, William M., Teede, Helena, Nolan, Christopher J., Peek, Michael J., Flack, Jeff R., McLean, Mark, Wong, Vincent, Hibbert, Emily, Kautzky-Willer, Alexandra, Harreiter, Jürgen, Backman, Helena, Gianatti, Emily, Sweeting, Arianne, Mohan, Viswanathan, Enticott, Joanne, Cheung, N. Wah
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Medical Society 08-06-2023
• Subjects: Age; Australia; Birth injuries; Birth weight; Body mass; Clinical trials; Complications of Pregnancy; Diabetes; Diabetes mellitus; Diabetes, Gestational - diagnosis; Diabetes, Gestational - therapy; Endocrinology; Fasting; Female; Gestation; Gestational diabetes; Glucose; Glucose tolerance; Gynecology; Gynecology General; Humans; Hyperglycemia; Hypertension; Hypoglycemia; Infant, Newborn; Lean body mass; Medical research; Neonates; Obstetrics; Phototherapy; Pilot projects; Pre-eclampsia; Pre-Eclampsia - epidemiology; Pre-Eclampsia - prevention & control; Preeclampsia; Pregnancy; Pregnancy complications; Pregnancy Outcome; Quality of life; Risk factors; Stillbirth; Trauma; Womens health; Australia
• ISSN: 0028-4793; 1533-4406; 1533-4406
• DOI: 10.1056/NEJMoa2214956

Treatment of gestational diabetes before 20 weeks’ gestation led to a modestly lower incidence of a composite of adverse neonatal outcomes but no material differences in pregnancy-related hypertension or neonatal lean body mass.