Urethral reconstruction using the carbon dioxide laser: an experimental evaluation

In an effort to test the efficacy of the carbon dioxide laser in urethral reconstruction, patch graft urethroplasty was carried out comparing laser repair to microsurgical repair. The male Sprague Dawley rat was used as the model. An oval defect was created in the ventral urethra in 65 animals and r...

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Bibliographic Details
Published in:	The Journal of urology Vol. 142; no. 4; p. 1139
Main Authors:	Ganesan, G S, Poppas, D P, Devine, Jr, C J, Schlossberg, S M
Format:	Journal Article
Language:	English
Published:	United States 01-10-1989
Subjects:	Analysis of Variance Animals Carbon Dioxide Evaluation Studies as Topic Hypospadias - therapy Laser Therapy Male Microsurgery Postoperative Complications Rats Rats, Inbred Strains Skin Transplantation Suture Techniques Urethra
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Summary:	In an effort to test the efficacy of the carbon dioxide laser in urethral reconstruction, patch graft urethroplasty was carried out comparing laser repair to microsurgical repair. The male Sprague Dawley rat was used as the model. An oval defect was created in the ventral urethra in 65 animals and repaired with a full thickness preputial skin graft conventional microsurgical repair, laser assisted microsurgical repair, or laser repair with a protein solder. The success rate, defined as the number of animals surviving without complications at the end of 21 days, was 50, 20, and 65% respectively. In conclusion, laser assisted repair using the protein solder was significantly better than microsurgical repair (p less than 0.05).
ISSN:	0022-5347
DOI:	10.1016/S0022-5347(17)39013-4