Angiotensin-converting enzyme content of human spermatozoa and its release during capacitation
In this study, we demonstrated, by using known detergents, the presence of angiotensin-converting enzyme (ACE) within human spermatozoa. We determined that maximal angiotensin-converting activity is expressed by sperm incubated in capacitating conditions, whereas this activity is negligible in salin...
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| Published in: | Fertility and sterility Vol. 47; no. 6; p. 1000 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | English |
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United States
01-06-1987
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| Abstract | In this study, we demonstrated, by using known detergents, the presence of angiotensin-converting enzyme (ACE) within human spermatozoa. We determined that maximal angiotensin-converting activity is expressed by sperm incubated in capacitating conditions, whereas this activity is negligible in saline-incubated spermatozoa. We further demonstrated that not acrosomes but cytoplasmic residues contain ACE. Because follicular fluid provides the necessary conditions for a maximal angiotensin-converting activity and for capacitations' metabolic activation, we hypothesize that ACE may play its physiologic role within the female reproductive tract. |
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| AbstractList | In this study, we demonstrated, by using known detergents, the presence of angiotensin-converting enzyme (ACE) within human spermatozoa. We determined that maximal angiotensin-converting activity is expressed by sperm incubated in capacitating conditions, whereas this activity is negligible in saline-incubated spermatozoa. We further demonstrated that not acrosomes but cytoplasmic residues contain ACE. Because follicular fluid provides the necessary conditions for a maximal angiotensin-converting activity and for capacitations' metabolic activation, we hypothesize that ACE may play its physiologic role within the female reproductive tract. |
| Author | Scandellari, C Foresta, C Indino, M Manoni, F |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/3036607$$D View this record in MEDLINE/PubMed |
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| Snippet | In this study, we demonstrated, by using known detergents, the presence of angiotensin-converting enzyme (ACE) within human spermatozoa. We determined that... |
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| SubjectTerms | Adult Fluorescent Antibody Technique Humans Male Peptidyl-Dipeptidase A - analysis Sperm Capacitation Spermatozoa - enzymology Time Factors |
| Title | Angiotensin-converting enzyme content of human spermatozoa and its release during capacitation |
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