Mandibular lymphomas with sclerosis

• Published in: Oral surgery, oral medicine, oral pathology, oral radiology and endodontics Vol. 81; no. 3; pp. 321 - 327
• Main Authors: Ríos-Martín, Juan J., Villar-Rodríguez, José L., Vázquez-Ramírez, Francisco J., Illanes-Moreno, Matilde, Parra-Martín, José A., González-Cámpora, Ricardo, Galera-Davidson, Hugo
• Format: Journal Article
• Language: English
• Published: St. Louis, MO Mosby, Inc 01-03-1996; Elsevier
• Subjects: Biological and medical sciences; Dentistry; Facial bones, jaws, teeth, parodontium: diseases, semeiology; Humans; Immunoenzyme Techniques; Lymphoma, B-Cell - pathology; Lymphoma, Large B-Cell, Diffuse - pathology; Male; Mandibular Neoplasms - pathology; Medical sciences; Middle Aged; Otorhinolaryngology. Stomatology; Sclerosis; Tumors; Human; Immunohistochemistry; Mandible; Stomatology; Male; Malignant hemopathy; Non Hodgkin lymphoma; Differential diagnostic; Sclerosis; Case study; Pathology; Primitive; Ultrastructure; Lymphoproliferative syndrome; Adult
• ISSN: 1079-2104; 1528-395X
• DOI: 10.1016/S1079-2104(96)80332-5

Two cases of non-Hodgkin's lymphoma that show a sarcomatoid pattern within the jaw are described. Theirprimary origin in bone was demonstrated by radiologic studies. In one case, diagnosis was delayed because the clinical picture suggested inflammatory periodontal disease. In both cases, the histologic picture was similar to that of a sarcomatoid neoplasm with intense stromal sclerosis; hemimandibulectomy was performed in one case. The tumor contained cells with large, irregular, sometimes lobulated nuclei and high mitotic activity, and perforated mandibular bone with infiltration into adjacent soft tissues. The lymphoid nature of these neoplasms was demonstrated by immunohistochemical and ultrastructural study.