Synthesis and antibacterial activity of 5-aryl-4-acyl-3-hydroxy-1-(2-hydroxyethyl)-3-pyrrolin-2-ones

5-Aryl-4-acyl-3-hydroxy-1-(2-hydroxyethyl)-3-pyrrolin-2-ones were synthesized using the reaction of ethanolamine with a mixture of aromatic aldehyde and methyl acylpyruvates. The antibacterial activity of the synthesized compounds was studied.

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Bibliographic Details
Published in:	Pharmaceutical chemistry journal Vol. 47; no. 10; pp. 536 - 538
Main Authors:	Gein, V. L., Odegova, T. F., Korol’, A. N., Varkentin, L. I., Bobyleva, A. A., Gein, L. F., Vakhrin, M. I.
Format:	Journal Article
Language:	English
Published:	Boston Springer US 2014 Springer
Subjects:	Antibacterial agents Ethanolamines Medicine Organic Chemistry Oxidoreductases Pharmacology/Toxicology Pharmacy synthesis antibacterial activity 5-aryl-4-acyl-3-hydroxy-1-(2-hydroxyethyl)-3-pyrrolin-2-ones
Online Access:	Get full text
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Description
Summary:	5-Aryl-4-acyl-3-hydroxy-1-(2-hydroxyethyl)-3-pyrrolin-2-ones were synthesized using the reaction of ethanolamine with a mixture of aromatic aldehyde and methyl acylpyruvates. The antibacterial activity of the synthesized compounds was studied.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	0091-150X 1573-9031
DOI:	10.1007/s11094-014-0999-5