Regression of hepatocellular adenomas and systemic inflammatory syndrome after cessation of estrogen therapy

We report a case of dramatic systemic inflammatory symptoms and biochemical signs of inflammation related to multiple hepatic adenomas that completely resolved after cessation of the oral contraceptive pill (OCP) and associated adenoma regression. This represents a case of dramatic symptoms that res...

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Bibliographic Details
Published in:	Hepatology (Baltimore, Md.) Vol. 66; no. 3; pp. 989 - 991
Main Authors:	Sinclair, Marie, Schelleman, Anthony, Sandhu, Daljean, Angus, Peter W.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01-09-2017
Subjects:	Adenoma Adenoma, Liver Cell - diagnostic imaging Adenoma, Liver Cell - surgery Adult Case reports Contraceptives, Oral, Hormonal - administration & dosage Contraceptives, Oral, Hormonal - adverse effects Estrogens - administration & dosage Estrogens - adverse effects Female Follow-Up Studies Hepatology Humans Inflammation Liver Liver cancer Liver Neoplasms - diagnostic imaging Liver Neoplasms - surgery Systemic Inflammatory Response Syndrome - diagnosis Systemic Inflammatory Response Syndrome - therapy Tomography, X-Ray Computed - methods Tumors Withholding Treatment
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Summary:	We report a case of dramatic systemic inflammatory symptoms and biochemical signs of inflammation related to multiple hepatic adenomas that completely resolved after cessation of the oral contraceptive pill (OCP) and associated adenoma regression. This represents a case of dramatic symptoms that resolved after estrogen withdrawal alone. (Hepatology 2017;66:989–991).
Bibliography:	Potential conflict of interest: Nothing to report. ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0270-9139 1527-3350
DOI:	10.1002/hep.29151