Amino acid content in several brain regions of the active and hibernating frog, Rana esculenta

• Published in: Comparative biochemistry and physiology. B, Comparative biochemistry Vol. 97; no. 3; p. 605
• Main Authors: Watanabe, M, Shimada, M, Watanabe, H, Nakanishi, M
• Format: Journal Article
• Language: English
• Published: England 1990
• Subjects: Amino Acids - metabolism; Animals; Brain - metabolism; Female; Hibernation - physiology; Male; Nerve Tissue Proteins - metabolism; Rana esculenta - metabolism
• ISSN: 0305-0491
• DOI: 10.1016/0305-0491(90)90167-R

1. Total free amino acid contents in the optic lobe and diencephalon increased significantly during hibernation. 2. Free glutamate + glutamine showed significant increases in the cerebral hemisphere, optic lobe, medulla oblongata and diencephalon. 3. Free aspartate + asparagine showed significant increases in the cerebral hemisphere, optic lobe, diencephalon and olfactory lobe. 4. GABA showed a significant change only in the medulla oblongata. 5. Total protein amino acid level in the cerebellum and olfactory lobe decreased significantly during hibernation and most of the amino acids decreased significantly in these regions. 6. The amino acid metabolism during amphibian hibernation differs from that of the mammal.