Dental and oral manifestations of celiac disease

• Published in: Medicina oral, patología oral y cirugía bucal Vol. 23; no. 6; pp. e639 - e645
• Main Authors: Cruz, I-T-S-A, Fraiz, F-C, Celli, A, Amenabar, J-M, Assunção, L-R-S
• Format: Journal Article
• Language: English
• Published: Spain Medicina Oral S.L 01-11-2018
• Subjects: Adolescent; Celiac Disease - complications; Child; Dentistry; Female; Humans; Male; Mouth Diseases - epidemiology; Mouth Diseases - etiology; Prevalence; Tooth Diseases - epidemiology; Tooth Diseases - etiology
• ISSN: 1698-6946; 1698-4447; 1698-6946
• DOI: 10.4317/medoral.22506

The objective of this study was to evaluate the dental and oral manifestations in patients with celiac disease.
The sample consisted of 40 patients with the disease and 40 without the disease matched by age in southern Brazil. The CD group included patients previously diagnosed by positive anti-endomysial (IgA) examination and confirmed by small intestine biopsy. The presence of dental enamel defects and dental caries was evaluated by a calibrated researcher according to AINE's and WHO's criteria, respectively. The history of recurrent aphthous ulcers and dry mouth was obtained through reporting. For the evaluation of the salivary flow, the saliva samples were obtained through the non-stimulated and stimulated saliva collection method.
There was a significant association between CD and dental enamel defects (OR=2.38, P=0.045) and dry mouth (OR=9.15, P=0.002). No difference was found for the report of recurrent aphthous ulcers and caries experience between the two groups. Patients with CD had normal pattern of unstimulated and stimulated saliva flow rates (0.67 ± 0.38 ml / min and 1.14 ± 0.47 ml / min, respectively). A higher occurrence of dental enamel defects was observed in patients with classic CD (P=0.054). Of the 1,962 permanent teeth, 59 presented dental enamel defects, 71.8% of which were in patients with CD (P=0.001), predominantly in molars (P=0.009).
CD increased the likelihood of dental enamel defects and dry mouth sensation. The oral examination can be an important auxiliary tool for the identification of cases of the disease.