Detection and Quantification of Rotenoids from Clitoria fairchildiana and its Lipids Profile

Detection and Quantification of Rotenoids from Clitoria fairchildiana and its Lipids Profile

This work describes the isolation and quantification of rotenoids from crude organic extracts of different parts of Clitoria fairchildiana R. A. Howard (Leguminosae) by HPLC-DAD. The lipid composition and the Artemia salina cytotoxic activities of the isolates were also conducted. Clitoriacetal (1),...

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Bibliographic Details
Published in:Natural product communications Vol. 11; no. 5; p. 631
Main Authors: Santos, Rauldenis A F, David, Jorge M, David, Juceni P
Format: Journal Article
Language:English
Published: United States 01-05-2016
Subjects:
Animals
Artemia
Clitoria - chemistry
Clitoria - toxicity
Lipids - analysis
Rotenone - analogs & derivatives
Rotenone - analysis
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Summary:This work describes the isolation and quantification of rotenoids from crude organic extracts of different parts of Clitoria fairchildiana R. A. Howard (Leguminosae) by HPLC-DAD. The lipid composition and the Artemia salina cytotoxic activities of the isolates were also conducted. Clitoriacetal (1), 6-deoxyclitoriacetal (2), stemonal and stemonone were isolated by chromatographic procedures and identified by usual spectroscopic and spectrometric techniques. Clitoriacetal and 6-deoxyclitoriacetal were not found in all parts of the plant, such as leaves and petals, but in the roots they occur in higher concentration. The activity against brine shrimp revealed that the root extract (LD50 = 158 ppm) was the more active.
ISSN:1934-578X
DOI:10.1177/1934578X1601100519