Dyshidrotic Eczema and Its Relationship to Metal Allergy

• Published in: Current problems in dermatology Vol. 51; p. 80
• Main Author: Nishizawa, Aya
• Format: Journal Article
• Language: English
• Published: Switzerland 01-01-2016
• Subjects: Dermatitis, Allergic Contact - diagnosis; Dermatitis, Allergic Contact - etiology; Dermatitis, Allergic Contact - physiopathology; Dermoscopy; Eczema, Dyshidrotic - complications; Eczema, Dyshidrotic - diagnostic imaging; Eczema, Dyshidrotic - pathology; Eczema, Dyshidrotic - physiopathology; Hand Dermatoses - complications; Hand Dermatoses - diagnostic imaging; Hand Dermatoses - pathology; Hand Dermatoses - physiopathology; Humans; Hypersensitivity - diagnosis; Hypersensitivity - etiology; Metals - adverse effects; Patch Tests; Sweat Glands - diagnostic imaging; Sweat Glands - pathology; Tomography, Optical Coherence
• ISSN: 1662-2944
• DOI: 10.1159/000446785

Dyshidrotic eczema, also known as dyshidrotic dermatitis or pompholyx, is characterized by pruritic, small tense vesicles mainly on the palmoplantar region and lateral and ventral surfaces of the fingers. While its etiology appears to be related to sweating, as dyshidrotic eczema often occurs in an individual with hyperhidrosis, and the spring allergy season, histologic examination shows an eczematous reaction around the sweat ducts which is not associated with abnormalities of the sweat ducts. More recently, the nomenclature of 'acute and recurrent vesicular hand dermatitis' has been proposed to reflect clinical features of dyshidrotic eczema. Although the exact etiology of dyshidrotic eczema remains unknown, given the presence of metal allergy in patients with dyshidrotic eczema and the improvement of the symptoms by removing metal allergen, metal allergy is regarded as one of the important potential etiologic factors for dyshidrotic eczema.