Chromosomal anomalies exclusive of telomeric associations in giant cell tumor of bone

The occurrence of telomeric associations in giant cell tumor of bone is well recognized. However, there has been little emphasis on clonal structural abnormalities that may be seen in addition to or in the absence of telomeric associations. Two cases of giant cell tumor of bone are presented in this...

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Bibliographic Details
Published in:	Cancer genetics and cytogenetics Vol. 88; no. 2; pp. 163 - 166
Main Authors:	McComb, Erin N., Johansson, Sonny L., Neff, James R., Nelson, Mari, Bridge, Julia A.
Format:	Journal Article
Language:	English
Published:	New York, NY Elsevier Inc 01-06-1996 Elsevier Science
Subjects:	Adult Biological and medical sciences Bone Neoplasms - genetics Chromosome Aberrations Diseases of the osteoarticular system Female Gene Deletion Giant Cell Tumor of Bone - genetics Humans Karyotyping Medical sciences Translocation, Genetic - genetics Tumors of striated muscle and skeleton Chromosomal aberration Human Association Giant cell tumor Diseases of the osteoarticular system Tumor Bone Telomer
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Summary:	The occurrence of telomeric associations in giant cell tumor of bone is well recognized. However, there has been little emphasis on clonal structural abnormalities that may be seen in addition to or in the absence of telomeric associations. Two cases of giant cell tumor of bone are presented in this study demonstrating clonal karyotypic anomalies other than telomeric association with a review of previously reported cases showing similar findings.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0165-4608 1873-4456
DOI:	10.1016/0165-4608(95)00362-2