An experimental model to investigate the dynamics of wound contraction

An excisional wound model in the Hooded Lister rat is described. The methods used to inflict, measure and characterise the process of wound contraction are comprehensively discussed. The model is shown to be reliable, reproducible and capable of detecting the effect of systemically administered pred...

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Bibliographic Details
Published in:	British journal of plastic surgery Vol. 48; no. 4; pp. 189 - 197
Main Authors:	Cross, S.E., Naylor, L., Coleman, R.A., Teo, T.C.
Format:	Journal Article
Language:	English
Published:	Oxford Elsevier Ltd 01-06-1995 Elsevier
Subjects:	Animals Biological and medical sciences Female Guinea Pigs Male Medical sciences Models, Biological Prednisolone - pharmacology Rats Rats, Inbred Strains Rats, Sprague-Dawley Skin - pathology Skin plastic surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Wound Healing - drug effects Wound Healing - physiology Skin disease Vertebrata Mammalia Rat Dynamics Animal Rodentia Experimental study Trauma Wound Contraction
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Summary:	An excisional wound model in the Hooded Lister rat is described. The methods used to inflict, measure and characterise the process of wound contraction are comprehensively discussed. The model is shown to be reliable, reproducible and capable of detecting the effect of systemically administered prednisolone.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0007-1226 1465-3087
DOI:	10.1016/0007-1226(95)90001-2