Successful treatment of post-exertion acute myocardial infarction by primary angioplasty and stenting in a patient with antiphospholipid antibody syndrome

• Published in: Blood coagulation & fibrinolysis Vol. 15; no. 1; pp. 95 - 98
• Main Authors: Musuraca, Gerardo, Imperadore, Ferdinando, Terraneo, Clotilde, De Girolamo, Piergiuseppe, Cemin, Claudio, Bonmassari, Roberto, Vergara, Giuseppe
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Lippincott Williams & Wilkins, Inc 01-01-2004; The Scientist
• Subjects: Angioplasty, Balloon, Coronary; Antiphospholipid Syndrome - complications; Biological and medical sciences; Blood coagulation. Blood cells; Exercise Test - adverse effects; Fundamental and applied biological sciences. Psychology; Hematologic and hematopoietic diseases; Humans; Male; Medical sciences; Middle Aged; Molecular and cellular biology; Myocardial Infarction - etiology; Myocardial Infarction - therapy; Platelet diseases and coagulopathies; Pulmonary Embolism - drug therapy; Pulmonary Embolism - etiology; Stents; Treatment Outcome; Venous Thrombosis - drug therapy; Venous Thrombosis - etiology; Warfarin - administration & dosage; Physical exercise; Human; Myocardial infarction; Immunopathology; Antiphospholipid antibody syndrome; Angioplasty; Acute; Instrumentation therapy; Cardiovascular disease; Autoimmune disease; Hemopathy; Instrumental dilatation; Myocardial disease; exercise test; Percutaneous route; Vascular disease; antiphospholipid syndrome; Platelet; percutaneous transluminal coronary angioplasty; Heart disease; Primary; acute myocardial infarction
• ISSN: 0957-5235; 1473-5733
• DOI: 10.1097/00001721-200401000-00015

Antiphospholipid syndrome is a disorder characterized by arterial and venous thromboses, thrombocytopaenia and stroke. Acute myocardial infarction is rarely associated with this syndrome. The treatment of these patients is a clinical challenge. This report is about a patient with antiphospholipid syndrome presenting with an acute myocardial infarction after an exercise test. The infarct-related coronary artery was successfully revascularized by primary angioplasty and stenting without any major bleeding complications. We think that the physical exertion could have favoured acute coronary thrombosis in this particular setting.