Fatal interaction between ritonavir and MDMA

The death of a patient indicates that ingestion of Ecstasy in recreational amounts by a person takign ritonavir could lead to toxic effects due to a high plasma concentration of the Ecstasy.

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Bibliographic Details
Published in:	The Lancet (British edition) Vol. 352; no. 9142; pp. 1751 - 1752
Main Authors:	Henry, JA, Hill, IR
Format:	Journal Article
Language:	English
Published:	London Elsevier Ltd 28-11-1998 Lancet Elsevier Limited
Subjects:	Acquired Immunodeficiency Syndrome - drug therapy Adult Anti-HIV Agents - poisoning Biological and medical sciences Drug abuse Drug Interactions Drug Therapy, Combination Fatal Outcome Fatalities Hallucinogens - poisoning Heart Arrest - chemically induced Human viral diseases Humans Infectious diseases Ingestion Liver Diseases, Alcoholic - complications Male Medical sciences N-Methyl-3,4-methylenedioxyamphetamine - poisoning Ritonavir Ritonavir - poisoning Side effects Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Human Immunopathology HIV-1 virus Ritonavir Retroviridae AIDS Pharmacovigilance Immune deficiency Lentivirus Infection Virus Case study Viral disease Ectasy Risk factor Antiviral Drug interaction Human immunodeficiency virus Pharmacokinetics
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Description
Summary:	The death of a patient indicates that ingestion of Ecstasy in recreational amounts by a person takign ritonavir could lead to toxic effects due to a high plasma concentration of the Ecstasy.
ISSN:	0140-6736 1474-547X
DOI:	10.1016/S0140-6736(05)79824-X