PREDICTORS OF MULTIFOCAL PAPILLARY THYROID CANCER. DO THEY EXIST?

• Published in: Acta endocrinologica (Bucharest, Romania : 2005) Vol. 18; no. 4; pp. 424 - 428
• Main Authors: Mazur, O V, Palamarchuk, V A, Tovkai, O A, Kuts, V V, Shidlovskyi, V O, Sheremet, M I, Levchuk, R D, Morozovych, I I, Lazaruk, O V, Cretoiu, D
• Format: Journal Article
• Language: English
• Published: Romania Carol Davila University Press 01-10-2022
• Subjects: General Endocrinology; predictors; multifocality; thyroid carcinoma; ultrasound diagnostics
• ISSN: 1841-0987; 1843-066X
• DOI: 10.4183/aeb.2022.424

The aim of this study is to analyze and identify the main predictors that may indicate multifocal growth of PTC.
The main and control groups included patients with the category of malignant multifocal process T1-3mN0Mx (n=109) and unifocal T1-T3N0Mx (n=50) respectively, who underwent thyroidectomy with lymphadenectomy.Ultrasound characteristics of the nodes, tissue changes of the thyroid gland were taken into account.
Fibrous changes can be considered as one of the risk factors of the presence of additional PTC lesion.
There is no unambiguity in the definition of predictors of multifocal PTC growth.
No clear predictors of multifocal PTC have been identified. It is advisable to improve the quality of ultrasound, to focus on single-focus PTC in patients with fibrinous changes in the thyroid gland at normal levels of TSH.