Nosocomial pneumonia in the pediatric trauma patient: A single center’s experience

• Published in: Critical care medicine Vol. 28; no. 10; pp. 3530 - 3533
• Main Authors: Patel, Jateen C, Mollitt, Daniel L, Pieper, Pam, Tepas, Joseph J
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins, Inc 01-10-2000; Lippincott
• Subjects: Adolescent; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Bacterial Infections - diagnosis; Bacterial Infections - drug therapy; Bacterial Infections - epidemiology; Bacterial Infections - etiology; Biological and medical sciences; Child; Child, Preschool; Cross Infection - diagnosis; Cross Infection - drug therapy; Cross Infection - epidemiology; Cross Infection - etiology; Emergency and intensive care: injuries, diseases due to physical agents. Diving. Drowning. Disaster medicine; Female; Humans; Incidence; Infection Control; Injury Severity Score; Intensive care medicine; Length of Stay - statistics & numerical data; Male; Medical sciences; Multiple Trauma - complications; Pneumonia - diagnosis; Pneumonia - drug therapy; Pneumonia - epidemiology; Pneumonia - etiology; Prospective Studies; Respiration, Artificial - adverse effects; Retrospective Studies; Risk Factors; Time Factors; Trauma Centers; Human; Nosocomial infection; Lung disease; Intensive care; Pneumonia; Prognosis; Respiratory disease; Critically ill; Artificial ventilation; Trauma; Intensive care unit; Infection; Bacteriosis; Complication; Frequency; Child; Mechanical ventilation
• ISSN: 0090-3493; 1530-0293
• DOI: 10.1097/00003246-200010000-00030

OBJECTIVESTo evaluate a single center’s experience with the frequency rate, patterns of occurrence, and impact on outcome of nosocomial pneumonia in the critically injured child.
DESIGNRetrospective review of prospectively collected data.
SETTINGLevel I university trauma center with a pediatric trauma intensive care unit.
PATIENTSA total of 523 consecutive critically injured children admitted to the pediatric intensive care unit during an 80-month interval.
MEASUREMENTS AND RESULTSThirty-five episodes of nosocomial pneumonia were identified in 29 children (frequency rate of 5.5%). The mean age of the children was 9.2 yrs, and the mean Injury Severity Score was 27 ± 9. In 91% of patients (26 children), nosocomial pneumonia was associated with mechanical ventilation. This represented a 13% frequency rate in injured children who were ventilated during the study period. The most common organisms recovered were Staphylococcus aureus (21%), Haemophilus influenzae (19%), Pseudomonas (11%), and Enterobacter (11%). Early pneumonia (diagnosed ≤7 days after injury) was predominantly caused by Haemophilus species. In contrast, Enterobacter and/or Pseudomonas were isolated primarily in late pneumonia (diagnosed >7 days after injury). Staphylococcus was prominent throughout the hospitalization. Overall, children with nosocomial pneumonia were more severely injured (Injury Severity Score 27 vs. 17, p < .001) and had a longer hospital stay (26 vs. 7 days, p < .001). Despite this, mortality (6.9% vs. 7.9%, p = NS) was not significantly different from injured children without pneumonia.
CONCLUSIONSIn this study of a single pediatric trauma center, nosocomial pneumonia occurred in a small but significant percentage of injured children. The frequency rate increased two- to three-fold with mechanical ventilation. Microbiology varied with day of onset. In contrast to the adult, mortality did not seem to be significantly altered by this complication. Analysis of additional pediatric trauma centers is encouraged to confirm these characteristics of nosocomial pneumonia in the injured child.