Laboratory Testing in Hyperthyroidism

Abstract The clinical diagnosis of hypo- or hyperthyroidism is difficult (full text available online: http://education.amjmed.com/pp1/272 ). Clinical symptoms and signs are often non-specific, and there is incomplete correlation between structural and functional thyroid gland changes. Laboratory tes...

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Bibliographic Details
Published in:	The American journal of medicine Vol. 125; no. 9; p. S2
Main Authors:	Grebe, Stefan K.G., MD, PhD, Kahaly, George J., MD, PhD
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-09-2012
Subjects:	Biomarkers - blood Female Humans Hyperthyroidism - blood Hyperthyroidism - diagnosis Hypothyroidism - blood Hypothyroidism - diagnosis Internal Medicine Male Pregnancy Pregnancy Complications - blood Pregnancy Complications - diagnosis Thyroid Hormones - blood Thyrotoxicosis - blood Thyrotoxicosis - diagnosis Thyrotropin - blood
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Summary:	Abstract The clinical diagnosis of hypo- or hyperthyroidism is difficult (full text available online: http://education.amjmed.com/pp1/272 ). Clinical symptoms and signs are often non-specific, and there is incomplete correlation between structural and functional thyroid gland changes. Laboratory testing is therefore indispensible in establishing the diagnosis of thyrotoxicosis. Similar considerations apply to treatment monitoring. Laboratory testing also plays a crucial role in establishing the most likely cause for a patient's hyperthyroidism. Finally, during pregnancy, when isotopic scanning is relatively contraindicated and ultrasound is more difficult to interpret, laboratory testing becomes even more important.
ISSN:	0002-9343 1555-7162
DOI:	10.1016/j.amjmed.2012.05.013