Clinical outcomes of two-stage total knee arthroplasty using articulating cement spacer in patients with infected arthritic knee: A comparison with arthroscopic surgery

• Published in: The knee Vol. 27; no. 2; pp. 444 - 450
• Main Authors: Seo, Seung-Suk, Kim, Chang-Wan, Lee, Chang-Rack, Park, Dae-Hyun, Kwon, Yong-Uk, Jung, Daewon, Kim, Dong-Seon
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-03-2020; Elsevier Limited
• Subjects: Activities of daily living; Antibiotics; Arthritis; Arthroplasty (knee); Arthroscopy; Cement; Clinical outcomes; Debridement; Disease control; Infection; Infections; Joint diseases; Joint replacement surgery; Joint surgery; Knee; Laboratories; Osteoarthritis; Outcomes; Patients; Quality of life; Studies; Surgery; Surgical techniques; Total knee arthroplasty; Transplants & implants; Infection; Total knee arthroplasty; Arthritis; Arthroscopy; Outcomes
• ISSN: 0968-0160; 1873-5800
• DOI: 10.1016/j.knee.2019.10.009

The aim of this study was to compare the functional outcomes and recurrence rate of infection between patients who underwent arthroscopic surgery and two-stage total knee arthroplasty (TKA) for infected arthritic knees.
A retrospective analysis was conducted on 52 patients (52 knees) with advanced knee joint arthritis who underwent arthroscopic surgery or two-stage TKA using articulating cement spacer (ACS) for knee joint infection between January 2009 and November 2013. Of the 52 patients (52 knees), 38 and 14 patients underwent arthroscopic surgery (AS group) and two-stage TKA using ACS (ACS-TKA group), respectively. Patient-reported outcomes (Knee Injury and Osteoarthritis Outcome Score (KOOS) and EuroQol-Visual Analog Scales (EQ-VAS)); range of motion; and recurrence rate of infection were evaluated.
Recurrence of infection was observed in 7/38 patients who underwent arthroscopic surgery, all of whom received two-stage TKA using ACS. Regarding the functional outcomes of the ACS-TKA group obtained before conversion to TKA and those of the AS group obtained six months after arthroscopic surgery, the former group had better outcomes for KOOS pain, KOOS activities of daily living, KOOS quality of life, and EQ-VAS. Regarding the functional outcomes of the ACS-TKA group obtained during the last follow-up and after conversion to TKA and those of the AS group who underwent TKA after arthroscopic surgery, no significant between-group differences were observed. The infection recurrence rate was higher in the AS than in the ACS-TKA group.
Considering infection control and functional outcomes, two-stage TKA using ACS can be an effective alternative treatment for patients with infected arthritic knees.